A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information.* Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic.* Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics.* Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.

Epithelial and Nonepithelial Transport and RegulationGeneral Principles of Epithelial and Nonepithelial TransportTransport RegulationStructural and Functional Organization of the KidneyStructural OrganizationFunctional OrganizationRenal Differentiation and GrowthFluid and Electrolyte Regulation and DysregulationRegulation and Disorders of Sodium Chloride HomeostasisRegulation and Disorders of Water HomeostasisRegulation and Disorders of Potassium Homeostasis Regulation and Disorders of Acid-Base HomeostasisRegulation and Disorders of Magnesium HomeostasisRegulation and Disorders of Calcium HomeostasisRegulation and Disorders of Phosphate HomeostasisRegulation and Disorders of Organic Solute HomeostasisRegulation and Disorders of Proteins and MacromoleculesPathophysiology of Renal Diease Clinical Presentation of Renal DerangementsMechanisms of Renal InjuryProgression of Renal Disease Physiological Considerations in the Management of Renal DiseaseFor full table of contents please see the link on the right below the blue bar "Look inside".