Beschreibung:
This book addresses the development, evaluation, and application of models of absolute risk- the probability of developing a specific disease over a specified time interval in the presence of competing causes of mortality. It discusses the development of appropriate statistical methods for estimating and applying absolute risk.
Introduction. Definitions and Basic Concepts for Survival Data in a Cohort without Covariates. Developing Absolute Risk Models from Cohort Data with Covariates. Estimating Absolute Risk from Case-Cohort and Nested Case-Control Data. Estimating Absolute Risk from Population-Based Case-Control and Registry Data. Evaluation of Adequacy of Model. Comparing Two Models. Special Topic: Disease Prognosis. Special Topic: Family-Based Designs