Computational Methods for Protein Structure Prediction and Modeling

Volume 2: Structure Prediction
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ISBN-13:
9781441922069
Veröffentl:
2010
Erscheinungsdatum:
01.12.2010
Seiten:
322
Autor:
Ying Xu
Gewicht:
481 g
Format:
234x156x18 mm
Sprache:
Englisch
Beschreibung:

Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.
This volume focuses on protein structure prediction methods and describes homology-based structure modeling, fold recognition of globular proteins, ab initio protein structure prediction, structure prediction of membrane proteins, prediction of structures of protein complexes, protein structure-based drug design, and structure prediction as a systems problem. It also contains a chapter listing Internet resources for protein structure/function characterization.
Protein Structure Prediction by Protein Threading.- De Novo Protein Structure Prediction.- Structure Prediction of Membrane Proteins.- Structure Prediction of Protein Complexes.- Structure-Based Drug Design.- Protein Structure Prediction as a Systems Problem.- Resources and Infrastructure for Structural Bioinformatics.

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