Beschreibung:
This book describes the embryonic development of the vertebrate inner ear in six chapters that span all aspects of inner ear development, from the induction of the otic placode through cellular morphogenesis, to the onset of auditory function. In each chapter, a particular aspect of development of the inner ear is examined in terms of both classic embryologic experiments and more recent advances using molecular biological techniques.
The development of the ear in the embryo and the molecular factorsthat influence its formation will be described in six chapters thatspan the period between otic placode and functional ear. The book willinterest scientists who study inner ear biology, as well asdevelopmental biologists who work in other systems but have aninterest in a review of the field of work on the developing ear aswell. This book might also be useful for clinicians who wish to knowmore about the development of the ear and about the genetic andmolecular factors that regulate its formation.
Developmental Neurobiology of the Ear: Current Status and Future Directions.- The Induction of the Otic Placode.- Morphogenesis of the Inner Ear.- Wiring the Ear to the Brain: The Molecular Basis of Neurosensory Development, Differentiation, and Survival.- Notch Signaling and Cell Fate Determination in the Vertebrate Inner Ear.- The Differentiation of Hair Cells.- Developmental Genes Associated with Human Hearing Loss.