RNA and Cancer
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ISBN-13:
9781441900210
Veröffentl:
2012
Erscheinungsdatum:
01.07.2012
Seiten:
310
Autor:
Jane Y. Wu
Format:
235x155x0 mm
Serie:
910, Cancer Treatment and Research
Sprache:
Englisch
Beschreibung:
Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer. RNA and Cancer focuses on the recent advances in our understanding of post-transcriptional gene regulation, especially RNA processing and its role in cancer development and treatment.
Review of the most current advances in understanding post-transcriptional gene regulation, with a special focus on RNA processing, and its role in cancer development and treatment.
Foreword.- Coupling between Transcription and Alternative Splicing.- Detection of Alternatively Spliced or Processed RNAs in Cancer using Oligonucleotide Microarray.- Cancer-associated Perturbations in Alternative Pre-messenger RNA Splicing.- Alternative Splicing of Tumor Suppressors and Oncogenes.- Imaging Alternative Splicing and Epithelial Plasticity in Tumor Cells and Tumors.- Alternative pre-mRNA splicing and regulation of cell death.- MIA melanoma?.- RNA localization/degradation.- RNA binding proteins and cancer.- Oligonucleotide cancer therapeutics.- Effects of anti-cancer drug on splicing.- Index.
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